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Gelatin and Other Unexpected Animal Products in Drugs, Dietary Supplements, and Cosmetics

by Thomas E. Billings

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Note: this page is a space-holder. The article is on hold and will not be posted online until at least 3 months after print publication. The links and references are provided here because of space limitations in print publishing.

 

Annotated Reference and Link List

 

Drug composition and animal products

·        eMC. Patient information leaflets for licensed medicines. Drug composition listings for the U.K.; enter medicine name in search box.

·        Vegan Society (U.K.). Animal-free medications. Source for the quote: "We do NOT advise you to stop taking medication or prescribed drugs for vegan reasons without consulting your GP."

·        Vegan Peace. Ingredients & Products. Glossary of animal and plant-derived substances.

 

Vegetarian/vegan-labeled products

·        Vegetarian Society (U.K.). Approved products and catering. Information on the Vegetarian Society Approved trademark; indicates that the product meets vegetarian criteria.

·        Vegan Society (U.K.). Vegan Logo. “The Vegan logo is a registered trademark and is a symbol of our Vegan 'Animal-free' Standards.”

 

Surveys of patients and health-care professionals

·        Vissamsetti B, Payne M, Payne S. (2012) Inadvertent prescription of gelatin-containing oral medication: its acceptability to patients. Postgraduate Medical Journal, doi:10.1136/postgradmedj-2011-130306. Abstract.

·        Warburton H, Payne M, Payne S. (2010) The problems of gelatine and prescribing urologically specific medication to a diverse population in the UK. An initial study. British Journal of Medical and Surgical Urology 3: 52—58. Journal table of contents.

 

Possible conflict with religious beliefs

·        Sattar S, Ahmed M, Majeed F, Petty F. (2004) Inert Medication Ingredients Causing Nonadherence Due to Religious Beliefs. Ann Pharmacother 38: 621-4. Abstract.

 

Widespread use of gelatin

·        Karim A, Bhat R. (2008) Gelatin alternatives for the food industry: recent developments, challenges and prospects. Trends in Food Science & Technology 19: 644-656. Journal table of contents.

·        Morrison N et al. (1999) Gelatin alternatives for the food industry. Progr Colloid Polym Sci 114: 127-131. Abstract.

·        Kralovec J, Zhang S, Zhang W, Barrow C. (2012) A review of the progress in enzymatic concentration and microencapsulation of omega-3 rich oil from fish and microbial sources. Food Chemistry 131: 639–644. Journal table of contents.

·        Barrow C, Nolan C, Jin Y. Stabilization of highly unsaturated fatty acids and delivery into foods. Lipid Technology. (2007) 19: 108–111. Abstract.

 

Gelatin from transgenic corn

·        Gelatin from corn, a first. Greener Magazine. (2007) Full text.

 

BSE risk

·        Berger C, Le Donne P, Windemann. (2005)  Use of substances of animal origin in pharmaceutics and compliance with the TSE-risk guideline - a market survey. Biologicals 33: 1-7. Journal table of contents.

·        Nemoto T, Horiuchi M, Ishiguro N,  Shinagawa M. (1999) Detection methods of possible prion contaminants in collagen and gelatin. Arch Virol 144: 177–184. Abstract.

·        European Food Safety Authority Biohazards Panel. (2006) Quantitative assessment of the human and animal BSE risk posed by gelatine with respect to residual BSE risk. The EFSA Journal 312: 1-29. Full text. (Source for quote used in paper.)

·        Grobben A,  Steele P, Somerville R, Taylor D. (2004) Inactivation of the bovine-spongiform-encephalopathy (BSE) agent by the acid and alkaline processes used in the manufacture of bone gelatine. Biotechnology and Applied Biochemistry 39(3): 329–338. Abstract.

 

BSE and virions

·        Manuelidis L. (2006) A 25 nm Virion Is the Likely Cause of Transmissible Spongiform Encephalopathies. Journal of Cellular Biochemistry 9999: 1–19. Full text.

·        Manuelidis L, Yu Z, Barquero N, Mullins B. Cells infected with scrapie and Creutzfeldt–Jakob disease agents produce intracellular 25-nm virus-like particles. (2007)  PNAS 104(6):  1965–1970. Full text.

 

Vegetarian capsules

·        Kua M et al. (2010) Performance qualification of a new hypromellose capsule: Part I. Comparative evaluation of physical, mechanical and processability quality attributes of Vcaps Plus®, Quali-V® and gelatin capsules. International Journal of Pharmaceutics 386: 30–41. Journal table of contents.

 

 

--Thomas E. (Tom) Billings

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